Structure of PDB 2j9l Chain E

Receptor sequence
>2j9lE (length=167) Species: 9606 (Homo sapiens) [Search protein sequence]
HKTLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRE
SQRLVGFVLRRDLIISIENARKKQDGVVSTSIIYFTEHSPPLPPYTPPTL
KLRNILDLSPFTVTDLTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKD
VLKHIAQMANFNEFLEV
3D structure
PDB2j9l Nucleotide Recognition by the Cytoplasmic Domain of the Human Chloride Transporter Clc-5
ChainE
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ATP E K587 L595 T596 Y617 S618 I722 T724 K726 D727 K10 L18 T19 Y40 S41 I145 T147 K149 D150 MOAD: Kd=90uM
External links
PDB RCSB:2j9l, PDBe:2j9l, PDBj:2j9l
PDBsum2j9l
PubMed17195847
UniProtP51795|CLCN5_HUMAN H(+)/Cl(-) exchange transporter 5 (Gene Name=CLCN5)

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