Structure of PDB 2icw Chain E

Receptor sequence
>2icwE (length=185) Species: 9606 (Homo sapiens) [Search protein sequence]
GDTRPRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRAV
TELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPKVT
VYPSKTQNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTF
QTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA
3D structure
PDB2icw Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC.
ChainE
Resolution2.41 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E W9 L11 F13 P56 D57 W61 Q70 R71 Y78 H81 N82 V85 W9 L11 F13 P56 D57 W61 Q70 R71 Y78 H81 N82 V85
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:2icw, PDBe:2icw, PDBj:2icw
PDBsum2icw
PubMed17220897
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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