Structure of PDB 2hrd Chain E

Receptor sequence
>2hrdE (length=252) Species: 99287 (Salmonella enterica subsp. enterica serovar Typhimurium str. LT2) [Search protein sequence]
SKSDVFHLGLTKNDLQGAQLAIVPGDPERVEKIAALMDKPVKLASHREFT
SWRAELDGKAVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPH
INVGDVLVTTASVRLDGASLHFAPMEFPAVADFACTTALVEAAKSIGATT
HVGVTASSDTFYPGQERYDTYSGRVVRRFKGSMEEWQAMGVMNYEMESAT
LLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVKIVVEAARR
LL
3D structure
PDB2hrd Crystal structure of the uridine phosphorylase from Salmonella typhimurium in complex with thymine and phosphate ion at 1.70A resolution
ChainE
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) R5030 R5048 R5091 R5168 I5220 V5221
Catalytic site (residue number reindexed from 1) R29 R47 R90 R167 I219 V220
Enzyme Commision number 2.4.2.3: uridine phosphorylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TDR E T5095 G5096 F5162 Q5166 R5168 E5196 M5197 I5220 T94 G95 F161 Q165 R167 E195 M196 I219
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004850 uridine phosphorylase activity
GO:0016757 glycosyltransferase activity
GO:0016763 pentosyltransferase activity
GO:0047847 deoxyuridine phosphorylase activity
Biological Process
GO:0009116 nucleoside metabolic process
GO:0009164 nucleoside catabolic process
GO:0009166 nucleotide catabolic process
GO:0044206 UMP salvage
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2hrd, PDBe:2hrd, PDBj:2hrd
PDBsum2hrd
PubMed
UniProtP0A1F6|UDP_SALTY Uridine phosphorylase (Gene Name=udp)

[Back to BioLiP]