Structure of PDB 2f54 Chain E

Receptor sequence
>2f54E (length=241) Species: 9606 (Homo sapiens) [Search protein sequence]
GVTQTPKFQVLKTGQSMTLQCAQDMNHEYMSWYRQDPGMGLRLIHYSVGA
GITDQGEVPNGYNVSRSTTEDFPLRLLSAAPSQTSVYFCASSYVGNTGEL
FFGEGSRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPD
HVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQD
PRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD
3D structure
PDB2f54 Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.
ChainE
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E E28 Y93 V94 G95 N96 E28 Y93 V94 G95 N96
External links
PDB RCSB:2f54, PDBe:2f54, PDBj:2f54
PDBsum2f54
PubMed16600963
UniProtP01850|TRBC1_HUMAN T cell receptor beta constant 1 (Gene Name=TRBC1)

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