Structure of PDB 2e2i Chain E

Receptor sequence
>2e2iE (length=213) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
QENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGR
PQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQE
KNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPK
HIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKS
ETSGRYASYRICM
3D structure
PDB2e2i Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
ChainE
Resolution3.41 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E V90 T117 S119 V88 T115 S117
Gene Ontology
Molecular Function
GO:0001054 RNA polymerase I activity
GO:0001055 RNA polymerase II activity
GO:0001056 RNA polymerase III activity
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0003968 RNA-dependent RNA polymerase activity
GO:0005515 protein binding
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0006360 transcription by RNA polymerase I
GO:0006361 transcription initiation at RNA polymerase I promoter
GO:0006362 transcription elongation by RNA polymerase I
GO:0006363 termination of RNA polymerase I transcription
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation at RNA polymerase II promoter
GO:0006368 transcription elongation by RNA polymerase II
GO:0006383 transcription by RNA polymerase III
GO:0006384 transcription initiation at RNA polymerase III promoter
GO:0006386 termination of RNA polymerase III transcription
GO:0042254 ribosome biogenesis
GO:0042790 nucleolar large rRNA transcription by RNA polymerase I
GO:0042797 tRNA transcription by RNA polymerase III
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005665 RNA polymerase II, core complex
GO:0005666 RNA polymerase III complex
GO:0005736 RNA polymerase I complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2e2i, PDBe:2e2i, PDBj:2e2i
PDBsum2e2i
PubMed17129781
UniProtP20434|RPAB1_YEAST DNA-directed RNA polymerases I, II, and III subunit RPABC1 (Gene Name=RPB5)

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