Structure of PDB 2ae8 Chain E

Receptor sequence
>2ae8E (length=171) Species: 158879 (Staphylococcus aureus subsp. aureus N315) [Search protein sequence]
AMIYQKQRNQLNISISDDQSPSHINTGVGFLNHMLTLFTFHSGLSLNIEA
QDDHHVTEDIGIVIGQLLLEMIKDKKHFVRYGTMYIPMDETLARVVVDIS
GRPYLSFNASLSKEKVGTFDTELVEEFFRAVVINARLTTHIDLIRGGNTH
HEIEAIFKAFSRALGIALTAT
3D structure
PDB2ae8 Crystal Structure of Imidazoleglycerol-phosphate Dehydratase from Staphylococcus aureus subsp. aureus N315
ChainE
Resolution2.01 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 4.2.1.19: imidazoleglycerol-phosphate dehydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG E H36 H158 E162 H33 H150 E154
BS02 MG E H62 E66 H54 E58
BS03 MG E E134 R137 E126 R129
Gene Ontology
Molecular Function
GO:0004424 imidazoleglycerol-phosphate dehydratase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0000105 L-histidine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2ae8, PDBe:2ae8, PDBj:2ae8
PDBsum2ae8
PubMed
UniProtP64373|HIS7_STAAN Imidazoleglycerol-phosphate dehydratase (Gene Name=hisB)

[Back to BioLiP]