Structure of PDB 1zfp Chain E

Receptor sequence
>1zfpE (length=98) Species: 9606 (Homo sapiens) [Search protein sequence]
KPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDV
QHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQ
3D structure
PDB1zfp Structural basis for the high affinity of amino-aromatic SH2 phosphopeptide ligands.
ChainE
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E R67 R86 S88 S90 S96 Q106 H107 F108 K109 L120 W121 R12 R31 S33 S35 S41 Q51 H52 F53 K54 L65 W66
BS02 ZN E H79 E152 H24 E97
External links
PDB RCSB:1zfp, PDBe:1zfp, PDBj:1zfp
PDBsum1zfp
PubMed9642078
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

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