Structure of PDB 1tzo Chain E

Receptor sequence
>1tzoE (length=553) Species: 191218 (Bacillus anthracis str. A2012) [Search protein sequence]
TVPDRDNDGIPDSLEVEGYTVDVKNKRTFLSPWISNIHEKKGLTKYKSSP
EKWSTASDPYSDFEKVTGRIDKNVSPEARHPLVAAYPIVHVDMENIILSK
NEDSQTRTISKNTSTSRTHTSEVHGNAEVHASFFDIGGSVSAGFSNSNSS
TVAIDHSLSLAGERTWAETMGLNTADTARLNANIRYVNTGTAPIYNVLPT
TSLVLGKNQTLATIKAKENQLSQILAPNNYYPSKNLAPIALNAQDSSTPI
TMNYNQFLELEKTKQLRLDTDQVYGNIATYNFENGRVRVDTGSNWSEVLP
QIQETTARIIFNGKDLNLVERRIAAVNPSDPLETTKPDMTLKEALKIAFG
FNEPNGNLQYQGKDITEFDFNFDQQTSQNIKNQLAELNATNIYTVLDKIK
LNAKMNILIRDKRFHYDRNNIAVGADESVVKEAHREVINSSTEGLLLNID
KDIRKILSGYIVEIEDTEGLKEVINDRYDMLNISSLRQDGKTFIDFKKYN
DKLPLYISNPNYKVNVYAVTKENTIINPSENGDTSTNGIKKILIFSKKGY
EIG
3D structure
PDB1tzo Structure of heptameric protective antigen bound to an anthrax toxin receptor: A role for receptor in pH-dependent pore formation
ChainE
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA E D177 D179 D181 I183 E188 P223 D4 D6 D8 I10 E15 P50
BS02 CA E D179 D181 E188 S222 P223 K225 D235 D6 D8 E15 S49 P50 K52 D62
Gene Ontology
Biological Process
GO:0051260 protein homooligomerization
Cellular Component
GO:0005576 extracellular region

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Biological Process
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Cellular Component
External links
PDB RCSB:1tzo, PDBe:1tzo, PDBj:1tzo
PDBsum1tzo
PubMed15326297
UniProtP13423|PAG_BACAN Protective antigen (Gene Name=pagA)

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