Structure of PDB 1tze Chain E

Receptor sequence
>1tzeE (length=98) Species: 9606 (Homo sapiens) [Search protein sequence]
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGND
VQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
3D structure
PDB1tze Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode.
ChainE
Resolution2.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E R67 R86 S88 S90 S96 H107 F108 K109 W121 R13 R32 S34 S36 S42 H53 F54 K55 W67
External links
PDB RCSB:1tze, PDBe:1tze, PDBj:1tze
PDBsum1tze
PubMed8673601
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

[Back to BioLiP]