Structure of PDB 1t13 Chain E

Receptor sequence
>1t13E (length=148) Species: 235 (Brucella abortus) [Search protein sequence]
TSFKIAFIQARWHADIVDEARKSFVAELAAKTGGSVEVEIFDVPGAYEIP
LHAKTLARTGRYAAIVGAAFVIDGGIYRHDFVATAVINGMMQVQLETEVP
VLSVVLTPHHFHESKEHHDFFHAHFKVKGVEAAHAALQIVSERSRIAA
3D structure
PDB1t13 Crystallographic studies on Decameric Brucella spp. Lumazine Synthase: A Novel Quaternary Arrangement Evolved for a New Function?
ChainE
Resolution2.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R88
Catalytic site (residue number reindexed from 1) R78
Enzyme Commision number 2.5.1.78: 6,7-dimethyl-8-ribityllumazine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 INI E L112 S113 L102 S103 PDBbind-CN: -logKd/Ki=7.38,Kd=0.042uM
BS02 INI E W22 G55 A56 Y57 E58 F80 V81 I82 W12 G45 A46 Y47 E48 F70 V71 I72 PDBbind-CN: -logKd/Ki=7.38,Kd=0.042uM
Gene Ontology
Molecular Function
GO:0000906 6,7-dimethyl-8-ribityllumazine synthase activity
GO:0016740 transferase activity
Biological Process
GO:0009231 riboflavin biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0009349 riboflavin synthase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1t13, PDBe:1t13, PDBj:1t13
PDBsum1t13
PubMed16165152
UniProtP61711|RISB2_BRUAB 6,7-dimethyl-8-ribityllumazine synthase 2 (Gene Name=ribH2)

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