Structure of PDB 1s9d Chain E

Receptor sequence
>1s9dE (length=193) Species: 9606 (Homo sapiens) [Search protein sequence]
KTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGL
NKTAIGDYLGEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGE
AQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSYSVIMLNTDLHNPNVRD
KMGLERFVAMNRGINEGGDLPEELLRNLYDSIRNEPFKIPEDD
3D structure
PDB1s9d Structural Snapshots of the Mechanism and Inhibition of a Guanine Nucleotide Exchange Factor
ChainE
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 AFB E Y190 M194 Y134 M138
Gene Ontology
Molecular Function
GO:0005085 guanyl-nucleotide exchange factor activity
Biological Process
GO:0032012 regulation of ARF protein signal transduction

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:1s9d, PDBe:1s9d, PDBj:1s9d
PDBsum1s9d
PubMed14654833
UniProtQ99418|CYH2_HUMAN Cytohesin-2 (Gene Name=CYTH2)

[Back to BioLiP]