Structure of PDB 1ppl Chain E

Receptor sequence
>1pplE (length=323) Species: 5079 (Penicillium janthinellum) [Search protein sequence]
AASGVATNTPTANDEEYITPVTIGGTTLNLNFDTGSADLWVFSTELPASQ
QSGHSVYNPSATGKELSGYTWSISYGDGSSASGNVFTDSVTVGGVTAHGQ
AVQAAQQISAQFQQDTNNDGLLGLAFSSINTVQPQSQTTFFDTVKSSLAQ
PLFAVALKHQQPGVYDFGFIDSSKYTGSLTYTGVDNSQGFWSFNVDSYTA
GSQSGDGFSGIADTGTTLLLLDDSVVSQYYSQVSGAQQDSNAGGYVFDCS
TNLPDFSVSISGYTATVPGSLINYGPSGDGSTCLGGIQSNSGIGFSIFGD
IFLKSQYVVFDSDGPQLGFAPQA
3D structure
PDB1ppl Crystallographic analysis of transition-state mimics bound to penicillopepsin: phosphorus-containing peptide analogues.
ChainE
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.23.20: penicillopepsin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1Z7 E D33 Y75 G76 D77 D213 G215 T216 T217 Y274 I297 D33 Y75 G76 D77 D213 G215 T216 T217 Y274 I297 MOAD: Ki=2.8nM
PDBbind-CN: -logKd/Ki=8.55,Ki=2.8nM
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ppl, PDBe:1ppl, PDBj:1ppl
PDBsum1ppl
PubMed1606144
UniProtP00798|PEPA1_PENJA Penicillopepsin-1

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