Structure of PDB 1nqw Chain E

Receptor sequence
>1nqwE (length=154) Species: 63363 (Aquifex aeolicus) [Search protein sequence]
MQIYEGKLTAEGLRFGIVASRFNHALVDRLVEGAIDCIVRHGGREEDITL
VRVPGSWEIPVAAGELARKEDIDAVIAIGVLIRGATPHFDYIASEVSKGL
ANLSLELRKPITFGVITADTLEQAIERAGTKHGNKGWEAALSAIEMANLF
KSLR
3D structure
PDB1nqw A structure-based model of the reaction catalyzed by lumazine synthase from Aquifex aeolicus.
ChainE
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H88
Catalytic site (residue number reindexed from 1) H88
Enzyme Commision number 2.5.1.78: 6,7-dimethyl-8-ribityllumazine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5YL E F113 R127 K135 F113 R127 K135
BS02 5YL E F22 G55 S56 W57 E58 V80 L81 I82 G84 A85 T86 F22 G55 S56 W57 E58 V80 L81 I82 G84 A85 T86
Gene Ontology
Molecular Function
GO:0000906 6,7-dimethyl-8-ribityllumazine synthase activity
GO:0016740 transferase activity
Biological Process
GO:0009231 riboflavin biosynthetic process
Cellular Component
GO:0005829 cytosol
GO:0009349 riboflavin synthase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1nqw, PDBe:1nqw, PDBj:1nqw
PDBsum1nqw
PubMed12684006
UniProtO66529|RISB_AQUAE 6,7-dimethyl-8-ribityllumazine synthase (Gene Name=ribH)

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