Structure of PDB 1mzn Chain E

Receptor sequence
>1mznE (length=224) Species: 9606 (Homo sapiens) [Search protein sequence]
NEDMPVERILEAELAVEPKTETYVEANNDPVTNICQAADKQLFTLVEWAK
RIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHR
NSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLS
NPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLE
HLFFFKLIGDTPIDTFLMEMLEAP
3D structure
PDB1mzn Molecular Recognition of Agonist Ligands by RXRs
ChainE
Resolution1.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E V2280 K2284 Q2297 V2298 R2302 T2449 F2450 E2453 P2458 V46 K50 Q63 V64 R68 T215 F216 E219 P224
BS02 BM6 E I2268 A2272 Q2275 N2306 L2309 I2310 F2313 R2316 L2326 C2432 I34 A38 Q41 N72 L75 I76 F79 R82 L92 C198
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003707 nuclear steroid receptor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1mzn, PDBe:1mzn, PDBj:1mzn
PDBsum1mzn
PubMed11981034
UniProtP19793|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)

[Back to BioLiP]