Structure of PDB 1lau Chain E

Receptor sequence
>1lauE (length=228) Species: 10298 (Human alphaherpesvirus 1) [Search protein sequence]
LDWTTFRRVFLIDDAWRPLMEPELANPLTAHLLAEYNRRCQTEEVLPPRE
DVFSWTRYCTPDEVRVVIIGQDPYHHPGQAHGLAFSVRANVPPPPSLRNV
LAAVKNCYPEARMSGHGCLEKWARDGVLLLNTTLTVKRGAAASHSRIGWD
RFVGGVIRRLAARRPGLVFMLWGTHAQNAIRPDPRVHCVLKFSHPSPLSK
VPFGTCQHFLVANRYLETRSISPIDWSV
3D structure
PDB1lau The structural basis of specific base-excision repair by uracil-DNA glycosylase.
ChainE
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.27: uracil-DNA glycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E D88 P89 Y90 H91 H92 P111 S112 P213 L214 D72 P73 Y74 H75 H76 P95 S96 P197 L198
Gene Ontology
Molecular Function
GO:0004844 uracil DNA N-glycosylase activity
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair

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Molecular Function
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Biological Process
External links
PDB RCSB:1lau, PDBe:1lau, PDBj:1lau
PDBsum1lau
PubMed7845459
UniProtP10186|UNG_HHV11 Uracil-DNA glycosylase (Gene Name=UL2)

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