Structure of PDB 1fv1 Chain E

Receptor sequence
>1fv1E (length=190) Species: 9606 (Homo sapiens) [Search protein sequence]
GDTRPRFLQQDKYECHFFNGTERVRFLHRDIYNQEEDLRFDSDVGEYRAV
TELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTVQRRVEPKVT
VYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQN
GDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA
3D structure
PDB1fv1 Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteins.
ChainE
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E Y13 Y60 W61 F67 R71 Y78 H81 N82 V85 G86 F89 Y13 Y60 W61 F67 R71 Y78 H81 N82 V85 G86 F89
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:1fv1, PDBe:1fv1, PDBj:1fv1
PDBsum1fv1
PubMed11080454
UniProtQ30154|DRB5_HUMAN HLA class II histocompatibility antigen, DR beta 5 chain (Gene Name=HLA-DRB5)

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