Structure of PDB 1dlh Chain E

Receptor sequence
>1dlhE (length=188) Species: 9606 (Homo sapiens) [Search protein sequence]
TRPRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRAVTE
LGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPKVTVY
PSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGD
WTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA
3D structure
PDB1dlh Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide.
ChainE
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide E F13 Y47 D57 Y60 W61 L67 Q70 R71 Y78 H81 N82 V85 F11 Y45 D55 Y58 W59 L65 Q68 R69 Y76 H79 N80 V83
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:1dlh, PDBe:1dlh, PDBj:1dlh
PDBsum1dlh
PubMed8145819
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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