Structure of PDB 1br4 Chain E

Receptor sequence
>1br4E (length=781) Species: 9031 (Gallus gallus) [Search protein sequence]
AQKPLSDDEKFLFVDKNFVNNPLAQADWSAKKLVWVPSEKHGFEAASIKE
EKGDEVTVELQENGKKVTLSKDDIQKMNPPKFSKVEDMAELTCLNEASVL
HNLRERYFSGLIYTYSGLFCVVINPYKQLPIYSEKIIDMYKGKKRHEMPP
HIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSP
SFSYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIV
GANIETYLLEKSRAIRQAKDERTFHIFYYLIAGASEQMRNDLLLEGFNNY
TFLSNGHVPIPAQQDDEMFQETLEAMTIMGFTEEEQTSILRVVSSVLQLG
NIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDV
VQKAQTKEQADFAIEALAKAKFERLFRWILTRVNKALDASFLGILDIAGF
EIFEINSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGL
DLQPCIELIERPTNPPGVLALLDEECWFPKATDTSFVEKLIQEQGNHAKF
QKSKQLKDKTEFCILHYAGKVTYNASAWLTKNMDPLNDNVTSLLNQSSDK
FVADLWKDVDRIVGLFRTVGQLYKEQLTKLMTTLRNTNPNFVRCIIPNHE
KRAGKLDAHLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAAN
AIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDL
KITDVIIAFQAQCRGYLARKAFAKRQQQLGS
3D structure
PDB1br4 Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state.
ChainE
Resolution3.62 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S179 G180 T184 N242 S245 S246 G468 E470
Catalytic site (residue number reindexed from 1) S178 G179 T183 N229 S232 S233 G449 E451
Enzyme Commision number 3.6.1.32: Transferred entry: 5.6.1.8.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG E T184 S246 T183 S233
BS02 ADP E N125 P126 Y127 K128 G180 A181 G182 K183 T184 E185 N124 P125 Y126 K127 G179 A180 G181 K182 T183 E184
BS03 BEF E S179 G180 K183 N242 G468 S178 G179 K182 N229 G449
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:1br4, PDBe:1br4, PDBj:1br4
PDBsum1br4
PubMed9741621
UniProtP10587|MYH11_CHICK Myosin-11 (Gene Name=MYH11)

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