Structure of PDB 1br1 Chain E

Receptor sequence
>1br1E (length=787) Species: 9031 (Gallus gallus) [Search protein sequence]
AQKPLSDDEKFLFVDKNFVNNPLAQADWSAKKLVWVPSEKHGFEAASIKE
EKGDEVTVELQENGKKVTLSKDDIQKMNPPKFSKVEDMAELTCLNEASVL
HNLRERYFSGLIYTYSGLFCVVINPYKQLPIYSEKIIDMYKGKKRHEMPP
HIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSH
KGKQGPSFSYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFD
VTGYIVGANIETYLLEKSRAIRQAKDERTFHIFYYLIAGASEQMRNDLLL
EGFNNYTFLSNGHVPIPAQQDDEMFQETLEAMTIMGFTEEEQTSILRVVS
SVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRI
KVGRDVVQKAQTKEQADFAIEALAKAKFERLFRWILTRVNKALDASFLGI
LDIAGFEIFEINSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWN
FIDFGLDLQPCIELIERPTNPPGVLALLDEECWFPKATDTSFVEKLIQEQ
GNHAKFQKSKQLKDKTEFCILHYAGKVTYNASAWLTKNMDPLNDNVTSLL
NQSSDKFVADLWKDVDRIVGLFRTVGQLYKEQLTKLMTTLRNTNPNFVRC
IIPNHEKRAGKLDAHLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRY
EILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHL
EEERDLKITDVIIAFQAQCRGYLARKAFAKRQQQLGS
3D structure
PDB1br1 Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state.
ChainE
Resolution3.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S179 G180 T184 N242 S245 S246 G468 E470
Catalytic site (residue number reindexed from 1) S178 G179 T183 N235 S238 S239 G455 E457
Enzyme Commision number 3.6.1.32: Transferred entry: 5.6.1.8.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG E T184 S246 T183 S239
BS02 ALF E S179 K183 S245 S246 G468 S178 K182 S238 S239 G455
BS03 ADP E N125 P126 Y127 G180 G182 K183 T184 E185 N124 P125 Y126 G179 G181 K182 T183 E184
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:1br1, PDBe:1br1, PDBj:1br1
PDBsum1br1
PubMed9741621
UniProtP10587|MYH11_CHICK Myosin-11 (Gene Name=MYH11)

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