Structure of PDB 1axm Chain E

Receptor sequence
>1axmE (length=129) Species: 9606 (Homo sapiens) [Search protein sequence]
KPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKST
ETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFV
GLKKNGSCKRGPRTHYGQKAILFLPLPVS
3D structure
PDB1axm Structure of a heparin-linked biologically active dimer of fibroblast growth factor.
ChainE
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IDS E K113 Q127 K128 A129 K104 Q118 K119 A120
BS02 SGN E K112 K113 K118 K103 K104 K109
Gene Ontology
Molecular Function
GO:0008083 growth factor activity

View graph for
Molecular Function
External links
PDB RCSB:1axm, PDBe:1axm, PDBj:1axm
PDBsum1axm
PubMed9655399
UniProtP05230|FGF1_HUMAN Fibroblast growth factor 1 (Gene Name=FGF1)

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