Structure of PDB 1aw8 Chain E

Receptor sequence

>1aw8E (length=91) Species: 562 (Escherichia coli) [Search protein sequence]

cCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGA
AAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMK

3D structure

PDB

1aw8 Crystal structure of aspartate decarboxylase at 2.2 A resolution provides evidence for an ester in protein self-processing.

Chain

Resolution

2.2 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	Y58
Catalytic site (residue number reindexed from 1)	Y33
Enzyme Commision number	4.1.1.11: aspartate 1-decarboxylase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	E	G37 N41 E42 A43 Y58 V91 T92	G13 N17 E18 A19 Y34 V67 T68
BS02	peptide	E	A36 G37 I68 I69 S70 V71 N72 G73 A76 H77 V81 G82 D83 I84 V85 I87 A88 S89 F90 V91 T92 M93 D95 A98 W101 P103 N104 V105 A106 Y107 F108 N112	A12 G13 I44 I45 S46 V47 N48 G49 A52 H53 V57 G58 D59 I60 V61 I63 A64 S65 F66 V67 T68 M69 D71 A74 W77 P79 N80 V81 A82 Y83 F84 N88

Gene Ontology

	Molecular Function
GO:0004068	aspartate 1-decarboxylase activity

	Biological Process
GO:0006523	alanine biosynthetic process

External links

PDB	RCSB:1aw8, PDBe:1aw8, PDBj:1aw8
PDBsum	1aw8
PubMed	9546220
UniProt	P0A790\|PAND_ECOLI Aspartate 1-decarboxylase (Gene Name=panD)