Structure of PDB 1aqd Chain E

Receptor sequence
>1aqdE (length=187) Species: 9606 (Homo sapiens) [Search protein sequence]
RPRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRAVTEL
GRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPKVTVYP
SKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDW
TFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA
3D structure
PDB1aqd The class II MHC protein HLA-DR1 in complex with an endogenous peptide: implications for the structural basis of the specificity of peptide binding.
ChainE
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E F13 P56 D57 Y60 W61 Q64 R71 T77 Y78 H81 N82 F10 P53 D54 Y57 W58 Q61 R68 T74 Y75 H78 N79
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:1aqd, PDBe:1aqd, PDBj:1aqd
PDBsum1aqd
PubMed9351812
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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