Structure of PDB 148l Chain E

Receptor sequence
>148lE (length=162) Species: 10665 (Tequatrovirus T4) [Search protein sequence]
MNIFEMLRIDEGLRLKIYKDTEGYYEIGIGHLLTKSPSLNAAKSELDKAI
GRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALI
NMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVI
TTFRTGTWDAYK
3D structure
PDB148l A covalent enzyme-substrate intermediate with saccharide distortion in a mutant T4 lysozyme.
ChainE
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.17: lysozyme.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E Q105 M106 F114 N116 S117 K135 S136 R137 W138 Q141 K162 Q105 M106 F114 N116 S117 K135 S136 R137 W138 Q141 K162
BS02 MUB E E11 D20 Y24 E26 G30 L32 F104 Q105 E11 D20 Y24 E26 G30 L32 F104 Q105
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0009253 peptidoglycan catabolic process
GO:0016998 cell wall macromolecule catabolic process
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium
GO:0044659 viral release from host cell by cytolysis
Cellular Component
GO:0030430 host cell cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:148l, PDBe:148l, PDBj:148l
PDBsum148l
PubMed8266098
UniProtP00720|ENLYS_BPT4 Endolysin (Gene Name=E)

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