Structure of PDB 5it8 Chain DW

Receptor sequence
>5it8DW (length=94) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAIELDHDKVMNM
QAKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLQHIDFVRA
3D structure
PDB5it8 Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
ChainDW
Resolution3.12 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna DW R9 Q12 G13 K14 S17 R18 R19 R21 I29 Y31 P37 Q75 Q78 H88 R9 Q12 G13 K14 S17 R18 R19 R21 I29 Y31 P37 Q75 Q78 H88
BS02 rna DW K46 K83 K46 K83
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0009314 response to radiation
GO:0017148 negative regulation of translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:5it8, PDBe:5it8, PDBj:5it8
PDBsum5it8
PubMed27382179
UniProtP68919|RL25_ECOLI Large ribosomal subunit protein bL25 (Gene Name=rplY)

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