Structure of PDB 4v56 Chain DW

Receptor sequence
>4v56DW (length=79) Species: 562 (Escherichia coli) [Search protein sequence]
GGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRD
HTLFAKADGKVKFEVKGPKNRKFISIEAE
3D structure
PDB4v56 A steric block in translation caused by the antibiotic spectinomycin.
ChainDW
Resolution3.93 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna DW K71 P73 K66 P68
BS02 rna DW S8 R10 N11 G12 R13 D14 S15 E16 K18 R19 L20 V22 K23 E28 S29 V30 L31 R38 Q39 R40 G41 T42 G53 R54 D55 H56 F59 F68 R76 S3 R5 N6 G7 R8 D9 S10 E11 K13 R14 L15 V17 K18 E23 S24 V25 L26 R33 Q34 R35 G36 T37 G48 R49 D50 H51 F54 F63 R71
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0043022 ribosome binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0001558 regulation of cell growth
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042256 cytosolic ribosome assembly
GO:0090070 positive regulation of ribosome biogenesis
GO:1902626 assembly of large subunit precursor of preribosome
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Cellular Component
External links
PDB RCSB:4v56, PDBe:4v56, PDBj:4v56
PDBsum4v56
PubMed17696316
UniProtP0A7L8|RL27_ECOLI Large ribosomal subunit protein bL27 (Gene Name=rpmA)

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