Structure of PDB 4v9o Chain DV

Receptor sequence

>4v9oDV (length=689) Species: 83333 (Escherichia coli K-12)

ARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNATMDWMEQEQERGI
TITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVM
VYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKTR
LGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPADM
VELANEWHQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNNEI
ILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHA
SDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERFG
RIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDPDAPIILERMEF
PEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGM
GELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQSGG
RGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQL
KAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPV
LLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLS
EMFGYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIE

3D structure

• PDB: 4v9o Control of ribosomal subunit rotation by elongation factor G.
• Chain: DV
• Resolution: 2.9 Å

Enzymatic activity

• Enzyme Commision number: 3.6.5.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	DV	H18 H92 P121 E463 L464 K507 Q514 L591 T628 G629 G633 R637 L642 K643 G644 Q645 R671 S672 K675	H17 H81 P110 E452 L453 K496 Q503 L580 T617 G618 G622 R626 L631 K632 G633 Q634 R660 S661 K664
BS02	rna	DV	P328 F329 G331 R359 R362 K507 S509 L591	P317 F318 G320 R348 R351 K496 S498 L580
BS03	MG	DV	T24 T62	T23 T51

Gene Ontology

Molecular Function

• GO:0003746 translation elongation factor activity
• GO:0003924 GTPase activity
• GO:0005525 GTP binding
• GO:0016787 hydrolase activity
• GO:0097216 guanosine tetraphosphate binding

Biological Process

• GO:0006412 translation
• GO:0006414 translational elongation
• GO:0032790 ribosome disassembly

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol

External links

• PDB: RCSB:4v9o, PDBe:4v9o, PDBj:4v9o
• PDBsum: 4v9o
• PubMed: 23812721
• UniProt: P0A6M8|EFG_ECOLI Elongation factor G (Gene Name=fusA)