Structure of PDB 4u27 Chain DT

Receptor sequence
>4u27DT (length=93) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MIREERLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIKAAVQKL
FEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNL
3D structure
PDB4u27 Synergy of streptogramin antibiotics occurs independently of their effects on translation.
ChainDT
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna DT M1 K9 H15 S17 E18 K19 K40 N59 T60 K64 K66 Q72 R73 G75 R76 R77 S78 Y84 M1 K9 H15 S17 E18 K19 K40 N59 T60 K64 K66 Q72 R73 G75 R76 R77 S78 Y84
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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External links
PDB RCSB:4u27, PDBe:4u27, PDBj:4u27
PDBsum4u27
PubMed24957822
UniProtP0ADZ0|RL23_ECOLI Large ribosomal subunit protein uL23 (Gene Name=rplW)

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