Structure of PDB 8c3a Chain DS

Receptor sequence

>8c3aDS (length=70) Species: 5476 (Candida albicans)

RKKKVYTTPKKIKHKHRKHKLAVLTYYKVDNEGNVERLRRECPAPTCGAG
IFMANMKDRQYCGKCHLTLK

3D structure

• PDB: 8c3a New crystal system to promote screening for new eukaryotic inhibitors
• Chain: DS
• Resolution: 3.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	DS	R122 T128 T129 P130 K131 K132 K134 H135 H137 R138 K141 L142 Y147 R160 F173 M174 A175 M177 R180 Y182 C183 G184 K185 H187 T189	R1 T7 T8 P9 K10 K11 K13 H14 H16 R17 K20 L21 Y26 R39 F52 M53 A54 M56 R59 Y61 C62 G63 K64 H66 T68
BS02	ZN	DS	C163 C168 C186	C42 C47 C65

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0031386 protein tag activity
• GO:0031625 ubiquitin protein ligase binding

Biological Process

• GO:0006412 translation
• GO:0016567 protein ubiquitination
• GO:0019941 modification-dependent protein catabolic process
• GO:0042254 ribosome biogenesis

Cellular Component

• GO:0005576 extracellular region
• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8c3a, PDBe:8c3a, PDBj:8c3a
• PDBsum: 8c3a
• UniProt: Q5A109|RS31_CANAL Ubiquitin-ribosomal protein eS31 fusion protein (Gene Name=UBI3)