Structure of PDB 4v7m Chain DS

Receptor sequence
>4v7mDS (length=98) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
KFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKG
NKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREG
3D structure
PDB4v7m The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome.
ChainDS
Resolution3.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna DS R13 R15 N16 I18 K19 F87 Y92 Y94 E107 G108 R3 R5 N6 I8 K9 F77 Y82 Y84 E97 G98
BS02 rna DS R17 R25 F29 L32 K33 H34 Q38 G45 V46 T47 S50 A55 G60 N61 K62 T63 Y92 H95 R97 R7 R15 F19 L22 K23 H24 Q28 G35 V36 T37 S40 A45 G50 N51 K52 T53 Y82 H85 R87
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:4v7m, PDBe:4v7m, PDBj:4v7m
PDBsum4v7m
PubMed20154709
UniProtQ5SHQ4|RL18_THET8 Large ribosomal subunit protein uL18 (Gene Name=rplR)

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