Structure of PDB 5tbw Chain DR

Receptor sequence
>5tbwDR (length=91) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
AKRTKKVGITGKYGVRYGSSLRRQVKKLEIQQHARYDCSFCGKKTVKRGA
AGIWTCSCCKKTVAGGAYTVSTAAAATVRSTIRRLREMVEA
3D structure
PDB5tbw Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides.
ChainDR
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna DR A2 R4 T5 K6 K7 V8 G9 I10 G12 K13 G15 V16 R17 Y18 G19 S20 S21 R23 H34 R36 K44 R49 A51 K62 Y69 A1 R3 T4 K5 K6 V7 G8 I9 G11 K12 G14 V15 R16 Y17 G18 S19 S20 R22 H33 R35 K43 R48 A50 K61 Y68
BS02 ZN DR C39 C42 C57 C60 C38 C41 C56 C59
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0046872 metal ion binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0044391 ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:5tbw, PDBe:5tbw, PDBj:5tbw
PDBsum5tbw
PubMed29064494
UniProtP0CX25|RL43A_YEAST Large ribosomal subunit protein eL43A (Gene Name=RPL43A)

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