Structure of PDB 4v50 Chain DQ

Receptor sequence

>4v50DQ (length=117) Species: 562 (Escherichia coli)

ARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRR
QRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVF
DKVAFTALVEKAKAALA

3D structure

• PDB: 4v50 Structural basis for mRNA and tRNA positioning on the ribosome.
• Chain: DQ
• Resolution: 3.22 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	DQ	A1 R2 V3 K4 R5 G6 R10 R12 H13 K15 K21 G22 Y23 Y24 G25 R27 R29 V30 Y31 R32 V33 Q36 K40 A41 Y44 Y46 R47 D48 R49 R50 Q51 R52 K53 R54 Q55 F56 R57 Q58 W60 I61 N65 S74 Y75 S76 I79 N80 R91 K92 I93	A1 R2 V3 K4 R5 G6 R10 R12 H13 K15 K21 G22 Y23 Y24 G25 R27 R29 V30 Y31 R32 V33 Q36 K40 A41 Y44 Y46 R47 D48 R49 R50 Q51 R52 K53 R54 Q55 F56 R57 Q58 W60 I61 N65 S74 Y75 S76 I79 N80 R91 K92 I93

Gene Ontology

Molecular Function

• GO:0000900 mRNA regulatory element binding translation repressor activity
• GO:0003729 mRNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding
• GO:0070180 large ribosomal subunit rRNA binding

Biological Process

• GO:0000027 ribosomal large subunit assembly
• GO:0002181 cytoplasmic translation
• GO:0006412 translation
• GO:0017148 negative regulation of translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4v50, PDBe:4v50, PDBj:4v50
• PDBsum: 4v50
• PubMed: 17038497
• UniProt: P0A7L3|RL20_ECOLI Large ribosomal subunit protein bL20 (Gene Name=rplT)