Structure of PDB 4u1v Chain DL

Receptor sequence

>4u1vDL (length=143) Species: 83333 (Escherichia coli K-12) [Search protein sequence]

RLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGGGVRRGFE
GGQMPLYRRLPKFGFTSRKAAITAEIRLSDLAKVEGGVVDLNTLKAANII
GIQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE

3D structure

PDB

4u1v Synergy of streptogramin antibiotics occurs independently of their effects on translation.

Chain

Resolution

3.0 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	DL	L3 N4 T5 L6 S7 P8 E10 S12 K13 K14 G16 K17 R18 L19 G20 R21 G22 G24 S25 G28 K29 T30 G32 R33 G34 H35 K36 G37 Q38 K39 R41 S42 G43 R47 R48 F50 E51 G52 G53 Q54 M55 L57 Y58 R59 R60 L61 K63 F64 G65 F66 T67 S68 R69 K70 E76 R78 N99 Q104 K109 I111 L112 R126 T128 K129 G130	L2 N3 T4 L5 S6 P7 E9 S11 K12 K13 G15 K16 R17 L18 G19 R20 G21 G23 S24 G27 K28 T29 G31 R32 G33 H34 K35 G36 Q37 K38 R40 S41 G42 R46 R47 F49 E50 G51 G52 Q53 M54 L56 Y57 R58 R59 L60 K62 F63 G64 F65 T66 S67 R68 K69 E75 R77 N98 Q103 K108 I110 L111 R125 T127 K128 G129

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0019843	rRNA binding

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0015934	large ribosomal subunit
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:4u1v, PDBe:4u1v, PDBj:4u1v
PDBsum	4u1v
PubMed	24957822
UniProt	P02413\|RL15_ECOLI Large ribosomal subunit protein uL15 (Gene Name=rplO)