Structure of PDB 6hiw Chain DJ

Receptor sequence

>6hiwDJ (length=315) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]

VGYTPVNPDTSPMVAYSQYHWHYNLPQGMERPHSVNRTFAAPFQSNHSLV
NKYRGVWIEFDMHPAFSVALEPQLRKLPRGRTLPKTPAEEVIADYTALAP
LVDDEKTRDLWLAKVFQHCAFQRCGGAMELWERYCHQRFTAEGATAKPPL
SLVKSVLFYCNKTDNSGWRALFDRCLKDGWNYTPLFDTAQWSFMLKSIGR
MGDEDGVRAVLEEMLDVQADLDRVEARSVVIALNAVTNADVYEFVKKYLF
NFGERKVKFLRTTYSDLRGHGAGKLRIPLKENDNMYYHVCWHSSIRSPRQ
FSPRQLYFDYTPSTL

3D structure

PDB

6hiw Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.

Chain

Resolution

3.37 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	DJ	V10 G11 Y12 F52 N55 H56 S57 L58 K61 R63 D231 R232 E234 A235 R264 K265 F268 R270 T271 H279 K283	V1 G2 Y3 F43 N46 H47 S48 L49 K52 R54 D222 R223 E225 A226 R255 K256 F259 R261 T262 H270 K274
BS02	UTP	DJ	R132 K171 F202 K205 R209 R236 K283 L284 R285	R123 K162 F193 K196 R200 R227 K274 L275 R276

Gene Ontology

	Cellular Component
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005763	mitochondrial small ribosomal subunit

View graph for
Cellular Component

External links

PDB	RCSB:6hiw, PDBe:6hiw, PDBj:6hiw
PDBsum	6hiw
PubMed	30213880
UniProt	Q584U8

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