Structure of PDB 4wf1 Chain DH

Receptor sequence
>4wf1DH (length=149) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNIEFFEAR
RAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIA
DAVTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE
3D structure
PDB4wf1 Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome.
ChainDH
Resolution3.09 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna DH G24 Y25 N28 F29 G24 Y25 N28 F29
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:4wf1, PDBe:4wf1, PDBj:4wf1
PDBsum4wf1
PubMed25368144
UniProtP0A7R1|RL9_ECOLI Large ribosomal subunit protein bL9 (Gene Name=rplI)

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