Structure of PDB 4v7v Chain DG

Receptor sequence
>4v7vDG (length=176) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
SRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLT
FGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGN
VINLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAY
RRPEPYKGKGVRYADEVVRTKEAKKK
3D structure
PDB4v7v Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
ChainDG
Resolution3.2891 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna DG S1 R2 V3 A62 Q63 T66 A69 G107 H110 Q138 Q142 R148 Y156 K157 K159 K171 E172 K174 S1 R2 V3 A62 Q63 T66 A69 G107 H110 Q138 Q142 R148 Y156 K157 K159 K171 E172 K174
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0046677 response to antibiotic
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:4v7v, PDBe:4v7v, PDBj:4v7v
PDBsum4v7v
PubMed20876128
UniProtP0AG55|RL6_ECOLI Large ribosomal subunit protein uL6 (Gene Name=rplF)

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