Structure of PDB 4u24 Chain DG

Receptor sequence
>4u24DG (length=176) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
SRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLT
FGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGN
VINLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAY
RRPEPYKGKGVRYADEVVRTKEAKKK
3D structure
PDB4u24 Synergy of streptogramin antibiotics occurs independently of their effects on translation.
ChainDG
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna DG S2 R3 V4 N38 A63 G66 T67 A70 S110 Q139 G142 Q143 Y157 K158 K160 K172 K175 K176 S1 R2 V3 N37 A62 G65 T66 A69 S109 Q138 G141 Q142 Y156 K157 K159 K171 K174 K175
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0046677 response to antibiotic
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:4u24, PDBe:4u24, PDBj:4u24
PDBsum4u24
PubMed24957822
UniProtP0AG55|RL6_ECOLI Large ribosomal subunit protein uL6 (Gene Name=rplF)

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