Structure of PDB 4v56 Chain DF

Receptor sequence

>4v56DF (length=178) Species: 562 (Escherichia coli) [Search protein sequence]

AKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLD
NAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFE
RLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRG
LDITITTTAKSDEEGRALLAAFDFPFRK

3D structure

PDB

4v56 A steric block in translation caused by the antibiotic spectinomycin.

Chain

Resolution

3.93 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	DF	S23 V24 M25 Q26 Q62 K63 L65 K68 K87 T89 R91	S23 V24 M25 Q26 Q62 K63 L65 K68 K87 T89 R91
BS02	rna	DF	T34 N36 M37 G38 V39 T67 R70 K71 A74 G75 F76 I78 I84 K87 F121 M129 G130 R132 G150 L151 D152 T154 T156	T34 N36 M37 G38 V39 T67 R70 K71 A74 G75 F76 I78 I84 K87 F121 M129 G130 R132 G150 L151 D152 T154 T156

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0008097	5S rRNA binding
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:4v56, PDBe:4v56, PDBj:4v56
PDBsum	4v56
PubMed	17696316
UniProt	P62399\|RL5_ECOLI Large ribosomal subunit protein uL5 (Gene Name=rplE)

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