Structure of PDB 7r1o Chain DDD

Receptor sequence
>7r1oDDD (length=53) Species: 9606 (Homo sapiens) [Search protein sequence]
NMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFP
SPF
3D structure
PDB7r1o Dusquetide modulates innate immune response through binding to p62.
ChainDDD
Resolution2.202 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide DDD N125 V126 I127 D129 N132 D147 D149 N6 V7 I8 D10 N13 D28 D30
BS02 ZN DDD C128 C131 C154 C9 C12 C35
BS03 ZN DDD C142 C145 H160 H163 C23 C26 H41 H44
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:7r1o, PDBe:7r1o, PDBj:7r1o
PDBsum7r1o
PubMed35640615
UniProtQ13501|SQSTM_HUMAN Sequestosome-1 (Gene Name=SQSTM1)

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