Structure of PDB 7ahz Chain DDD

Receptor sequence

>7ahzDDD (length=56) Species: 8364 (Xenopus tropicalis) [Search protein sequence]

EPCVICQTRPKNGCIVHGRTGHLMACYTCAKKLKKRNKPCPVCREPIQMI
VLTYFS

3D structure

PDB

7ahz Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant.

Chain

DDD

Resolution

1.82 Å

3D
structure

Enzymatic activity

Enzyme Commision number

2.3.2.27: RING-type E3 ubiquitin transferase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ZN	DDD	C429 C432 C452 C455	C3 C6 C26 C29
BS02	ZN	DDD	H443 H448 C466 C469	H17 H22 C40 C43

Gene Ontology

	Molecular Function
GO:0042802	identical protein binding
GO:0061630	ubiquitin protein ligase activity

	Biological Process
GO:0043066	negative regulation of apoptotic process
GO:0051726	regulation of cell cycle

	Cellular Component
GO:0005634	nucleus

External links