Structure of PDB 8fiz Chain DD

Receptor sequence
>8fizDD (length=76) Species: 562 (Escherichia coli) [Search protein sequence]
TRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRDHTL
FAKADGKVKFEVKGPKNRKFISIEAE
3D structure
PDB8fiz A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery.
ChainDD
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna DD N12 R14 D15 S16 A18 K19 R20 K24 F26 G27 E29 A33 G34 S35 I36 T43 K44 G54 R55 H57 R77 K78 N3 R5 D6 S7 A9 K10 R11 K15 F17 G18 E20 A24 G25 S26 I27 T34 K35 G45 R46 H48 R68 K69
BS02 rna DD P74 N76 P65 N67
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0043022 ribosome binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0001558 regulation of cell growth
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042256 cytosolic ribosome assembly
GO:0090070 positive regulation of ribosome biogenesis
GO:1902626 assembly of large subunit precursor of preribosome
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:8fiz, PDBe:8fiz, PDBj:8fiz
PDBsum8fiz
PubMed36931247
UniProtP0A7L8|RL27_ECOLI Large ribosomal subunit protein bL27 (Gene Name=rpmA)

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