Structure of PDB 7pub Chain DD

Receptor sequence

>7pubDD (length=790) Species: 5702 (Trypanosoma brucei brucei)

RSGKARAFVFRDPSLRMMRAGSGYQQLRRMGMPMQVGMGWRKVDSFHANT
QYQHAWPLLSHDDLGNSDQSNNTKNIMYSMYMPKRNKGTAPWFRGADTYS
VKYCEQGRYEYQRYLMINRFPSEYKKHFLSFLSNIRMSSGSATIPQEALH
WLLRMIVDNFNPQHVHYIAAMKTLQSAGELDMARDVWKIMERQQTWPCTA
TICAYLDVCVEAGEKTWAMEAWNRYCTELKFLEPGEVDPKPISRVPFSLT
REELLYLPKWKKHFDHDPNLDVMDLNRFNRTREVYLRMAQVMLAGGERNA
FQHFFTKLEEAMLNKPTPVPEPPNPHLVRRPRWAPYEHCKSVHHSPWRLQ
NNGRALALGPPVTIEDEMQSRFFSNDQFLVHSVKEVLRIVLQEHKRAHPT
ECTRCKTEAFFYKTKDADETLKFCDDLIERLFASLGVRLSNLNTSSLLST
ILEVFRVVGKESGAALLQRANEFLERKASLGDAEGSRENLTASNYLQVLS
GFADESAFVYNTKKDGTCQYKTGFDPRTTMRHLADVVQEIAGNPHVTWAA
DMHLQVVETMVGCGTMKANDYFVRNVLRQFSWDSRFLEALYVEYRRQDDV
DMWAELTKRALVWTARYNAPASERLRRLIEDDYDTIRVQTRTFRELAVFQ
FRDVEERRHSRDVVNELPNPWYDYVAHALPFPDRDAGYPDEYGDLGQWRA
PGGPGSPVRGPRGYTAEWRDLRNPMRPPEFPTPWERKYRQYARGQHPSYD
MVYAGPMPEIFPMRRDFRKPTRWDFHDIEKQGKYRTSGPY

3D structure

• PDB: 7pub Mitoribosomal small subunit maturation involves formation of initiation-like complexes.
• Chain: DD
• Resolution: 3.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	DD	R11 S12 K14 A15 R16 A17 R21 P23 R26 A30 R38 M44 Q45 V46 G47 W50 R51 K52 F56 G75 R95 K97 D107 T108 Y109 K136 S143 S149 S151 A152 R339 R342 Q707 W708 A710 Y763 D772 K805	R1 S2 K4 A5 R6 A7 R11 P13 R16 A20 R28 M34 Q35 V36 G37 W40 R41 K42 F46 G65 R85 K87 D97 T98 Y99 K126 S133 S139 S141 A142 R329 R332 Q697 W698 A700 Y741 D750 K783

Gene Ontology

Biological Process

• GO:0000963 mitochondrial RNA processing

Cellular Component

• GO:0005737 cytoplasm
• GO:0005739 mitochondrion
• GO:0031019 mitochondrial mRNA editing complex

External links

• PDB: RCSB:7pub, PDBe:7pub, PDBj:7pub
• PDBsum: 7pub
• PubMed: 35042777
• UniProt: Q385L8