Structure of PDB 8fiz Chain DC

Receptor sequence

>8fizDC (length=94) Species: 562 (Escherichia coli) [Search protein sequence]

MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAIELDHDKVMNM
QAKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLQHIDFVRA

3D structure

PDB

8fiz A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery.

Chain

Resolution

3.8 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	DC	R9 K14 R18 R19 R21 Y31 Q78 H88	R9 K14 R18 R19 R21 Y31 Q78 H88

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0008097	5S rRNA binding
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation
GO:0009314	response to radiation
GO:0017148	negative regulation of translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:8fiz, PDBe:8fiz, PDBj:8fiz
PDBsum	8fiz
PubMed	36931247
UniProt	P68919\|RL25_ECOLI Large ribosomal subunit protein bL25 (Gene Name=rplY)