Structure of PDB 8cq7 Chain DC

Receptor sequence

>8cq7DC (length=130) Species: 5476 (Candida albicans) [Search protein sequence]

MVDATAPKKRTFKQFSFKGVDLKDLVEMPTEEFTKLCGARVRRRFSRGLD
SKPMGLIKKLRAARAATEPNERPAVVKTHLRNMIVVPEMIGSVVGVYNGK
VFNTVEIKPEMVGHYLGEFSITYTPVRHGR

3D structure

PDB

8cq7 Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement

Chain

Resolution

3.2 Å

3D
structure

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	DC	K18 G38 A39 R40 R42 R43 R44 R47 K59 K77 T78 H79 R81 N82 Y97 N98 G99 K100 F102 Y115 E118 T122 Y123 T124 V126 R127 H128	K18 G38 A39 R40 R42 R43 R44 R47 K59 K77 T78 H79 R81 N82 Y97 N98 G99 K100 F102 Y115 E118 T122 Y123 T124 V126 R127 H128
BS02	MG	DC	F119 I121	F119 I121

External links

PDB	RCSB:8cq7, PDBe:8cq7, PDBj:8cq7
PDBsum	8cq7
PubMed
UniProt	A0A1D8PK22\|RS15_CANAL Small ribosomal subunit protein uS19 (Gene Name=RPS15)