Structure of PDB 6hiw Chain DA

Receptor sequence
>6hiwDA (length=1557) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
SFKYATKLQHDEMRQPYYIHEKRYGIFSNERNIAKARRGLPFITPLYTKH
MNLWDTDTDASNNRFFRGYYYGQRELHQLLGRPHSLEATNADGSNDLSTY
EANTSQLYKGIPRPAITNLHYEPAWRYTLYQAGAHGAQLSNPRSPFTAKV
LGDELMQVRDIKSVEHCKAWFDRLQYLINLHYEAVGDIGEFKSRHTRHVH
EFFVAFHDALSSLDFRDTYLFDQFKAVRPPELSDLFGIFLEMEANYVHED
YCPRCSLPYSTTRYCGEGDVDTPFRKHRGRWAPHQKWGREWYDVVARRAE
ALWYRATEDPYFGTPQHTQRQAEALLKVYVQAKQRGKAIDFMNKLRGSVE
YLTGDITITTVMQESYDALLDTTPHPHLLTNGFTLESDAAKYTGEVNKAP
LSPLQFRIDMEMNKYRRQQKEEGVVRVPPALWRLDTSAIVPYKVDSKTRR
IVNWREVKEGIEKSFLSVGLPKEAYTGNEWREMLYLHDVIANREAKAAVL
EQQQKLDREKLKARERASLKGEKSSNSASNGIGIIFPDKDGYQVFFVDEA
SLRPFGIGASGTLFKAVARVYPSPAAVPYDDPVHGKQFLIDTTDETCHLF
GGFEHGDRLLLRAKSDEEEEVIVMGVSTEGSDAERMLCAMHVDTGKQRER
GIVFLGTDCIDIRERWESVRYAASAYVKGRVTLLESQRTAREEFMGQVVG
IRDGVLFVQWRLLKGGGSVLDRSVAVPIGDSTQVRELFVETKVLGVEPLQ
SPPSWRTPFRNDFAEERLKELQRAPFKREKYVSLIQGKYTPKVKKFGYTQ
HTTVDDFETKEYKDRLLSKQFFQNPQAFEVVPDRHERSVQFGGKWEYQRT
HGLPTVDRNELENGWSEVEPISDGEMKVIEQALRDISGPRPGNFVKPPSK
TKSLQLSESWWEPLGYGWEQHNEEQKALCDVTEQRLIDGSNLPFGGKLPP
FGTSYGMGERMRAIIEDYSKGFGLGPHGHSPTHDTIHYNTLNAEGERVRD
LGYTDALGRLFSEKLGDRDVHQWAVESCADGEADVRQLLLSLHEWRERGR
PPSLLLANVLSKYLEEEIAAFNKGIPENAPKLQLETSDGTLAHSGSGGSR
SGTMWADVDPTTFALHQASQSTRSTRCDEPFILHLVKRAKLGECVTNFTD
TAYIAHLESSVINEFHLALTKLVGKGISPTLLAQKTGQLHRGSVRVGGNV
VPFVKSRELSRLLERMGLTSESIAVITRGLANCPEQESVGDDFAVPVSLI
LSWDGPGQNEDKMVVHVLEELSLRNDGLVMDIQYAIRENKKNRRLRWEFV
TTLLPVFGGNEAKVEQLYSDYCDGKYVPNITVAVEAFIAFLHNATQHPET
YSASDYFDIDDGKSSTASGTGDQPSAGQYTTLKLLDPLEGPFVFDNVKVE
YIQTVERFRRHGIRAGPVMAPATGFIAANCKSLNYFTRRQEEVVYVTNDS
DQGLRRSLENSAYHKTIAANPALQYLLKARRGAALVETFNRFFYRTMPML
NFYQNVLKHYSETIQPLRQAAKSSTRGLARALESERSAAMEEFRRNSERY
WRNIIEG
3D structure
PDB6hiw Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
ChainDA
Resolution3.37 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna DA S40 F41 K42 K46 Q48 R70 K74 A75 R76 L79 P80 F81 R314 H316 R317 G318 R319 S1 F2 K3 K7 Q9 R31 K35 A36 R37 L40 P41 F42 R275 H277 R278 G279 R280
BS02 ZN DA C291 C294 C304 H323 C252 C255 C265 H284
Gene Ontology
Cellular Component
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit

View graph for
Cellular Component
External links
PDB RCSB:6hiw, PDBe:6hiw, PDBj:6hiw
PDBsum6hiw
PubMed30213880
UniProtQ57UJ2

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