Structure of PDB 4u24 Chain D3

Receptor sequence

>4u24D3 (length=64) Species: 83333 (Escherichia coli K-12) [Search protein sequence]

PKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVS
KGDLGLVIACLPYA

3D structure

PDB

4u24 Synergy of streptogramin antibiotics occurs independently of their effects on translation.

Chain

Resolution

2.9 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	D3	P2 K3 I4 K5 T6 R8 K12 R13 T17 G18 K19 K23 K25 H26 A27 N28 R30 H31 I32 L33 T34 K35 T38 K39 R40 R42 H43 L44 R45 M49 S51 K52 G53 D54 Y64	P1 K2 I3 K4 T5 R7 K11 R12 T16 G17 K18 K22 K24 H25 A26 N27 R29 H30 I31 L32 T33 K34 T37 K38 R39 R41 H42 L43 R44 M48 S50 K51 G52 D53 Y63

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:4u24, PDBe:4u24, PDBj:4u24
PDBsum	4u24
PubMed	24957822
UniProt	P0A7Q1\|RL35_ECOLI Large ribosomal subunit protein bL35 (Gene Name=rpmI)