Structure of PDB 9fcj Chain D

Receptor sequence
>9fcjD (length=312) Species: 9606 (Homo sapiens) [Search protein sequence]
VGLNNLGNTSYLNSILQVLYFCPGFKSGVKHLFNIISRKKYELICSLQSL
IISVEQLQASFLLNPEKYTDELATQPRRLLNTLRELNPMLQHDAQEVLQC
ILGNIQETCQLLKKGFELVEKLFQGQLVLRTRCLECESLTERREDFQDIS
VPVQEDMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMP
EVITIHLKCFAASGLSKINTPLLTPLKLSLEEWSTKPTNDSYGLFAVVMH
SGITISSGHYTASVKVTKEYEGKWLLFDDSEVKVTEEKDFLNSLSPSTSP
TSTPYLLFYKKL
3D structure
PDB9fcj Structural and Biochemical Insights into the Mechanism of Action of the Clinical USP1 Inhibitor, KSQ-4279.
ChainD
Resolution2.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN D C440 C443 C506 C509 C133 C136 C181 C184
BS02 JDA D L96 Q97 Y100 V156 Q160 F163 Y170 L748 F750 S753 L16 Q17 Y20 V54 Q58 F61 Y68 L275 F277 S280
External links
PDB RCSB:9fcj, PDBe:9fcj, PDBj:9fcj
PDBsum9fcj
PubMed39190802
UniProtO94782|UBP1_HUMAN Ubiquitin carboxyl-terminal hydrolase 1 (Gene Name=USP1)

[Back to BioLiP]