Structure of PDB 9f1n Chain D

Receptor sequence
>9f1nD (length=125) Species: 9606 (Homo sapiens) [Search protein sequence]
MNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKL
NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKP
GDDIVLMAEALEKLFLQKINELPTE
3D structure
PDB9f1n First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 46
ChainD
Resolution1.71 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1H9H D W81 P82 V87 N140 I146 W39 P40 V45 N98 I104
External links
PDB RCSB:9f1n, PDBe:9f1n, PDBj:9f1n
PDBsum9f1n
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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