Structure of PDB 9cc3 Chain D

Receptor sequence
>9cc3D (length=543) Species: 9606 (Homo sapiens) [Search protein sequence]
LLQEQLKIIKKELGLEKDDKDAIEEKFRERLKELVVPKHVMDVVDEELSK
LGLLDNHSSEFNVTRNYLDWLTSIPWGKYSNENLDLARAQAVLEEDHYGM
EDVKKRILEFIAVSQLRGSTQGKILCFYGPPGVGKTSIARSIARALNREY
FRFSVGGMTDVAEIKGHRRTYVGAMPGKIIQCLKKTKTENPLILIDEVDK
IDPSSALLELLDPEQNANFLDHYLDVPVDLSKVLFICTANVTDTIPEPLR
DRMEMINVSGYVAQEKLAIAERYLVPQARALCGLDESKAKLSSDVLTLLI
KQYCRESGVRNLQKQVEKVLRKSAYKIVSGEAESVEVTPENLQDFVGKPV
FTVERMYDVTPPGVVMGLAWTAMGGSTLFVETSLRRPQDKDGSLEVTGQL
GEVMKESARIAYTFARAFLMQHAPANDYLVTSHIHLHVPEGATPKDGPSA
GCTIVTALLSLAMGRPVRQNLAMTGEVSLTGKILPVGGIKEKTIAAKRAG
VTCIVLPAENKKDFYDLAAFITEGLEVHFVEHYREIFDIAFPD
3D structure
PDB9cc3 Structural and mechanistic studies on human LONP1 redefine the hand-over-hand translocation mechanism.
ChainD
Resolution3.23 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP D H491 Y492 P525 G526 V527 G528 K529 T530 Y661 Y673 V709 R710 H97 Y98 P131 G132 V133 G134 K135 T136 Y261 Y273 V309 R310
BS02 MG D D590 E591 D196 E197
External links
PDB RCSB:9cc3, PDBe:9cc3, PDBj:9cc3
PDBsum9cc3
PubMed38979310
UniProtP36776|LONM_HUMAN Lon protease homolog, mitochondrial (Gene Name=LONP1)

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