Structure of PDB 9bkd Chain D

Receptor sequence

>9bkdD (length=177) Species: 9606 (Homo sapiens) [Search protein sequence]

PVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLA
KIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLK
IEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRL
DSQKHIDFSLRSPYGGGRPGRVKRKNA

3D structure

PDB

9bkd Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit.

Chain

Resolution

2.6 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	D	P2 V3 A4 R5 S6 W7 V8 C9 R10 K11 T12 T15 R17 R18 P19 F20 K22 R38 N39 K40 R41 R45 F72 E73 A76 R79 R80 S122 H125 R127 R131 Q132 R133 H134 Q140 N143 I144 S146 F147 I148 R150 S153 R162 P164 Y165 R169 G171 R172 V173 K174 N177	P1 V2 A3 R4 S5 W6 V7 C8 R9 K10 T11 T14 R16 R17 P18 F19 K21 R37 N38 K39 R40 R44 F71 E72 A75 R78 R79 S121 H124 R126 R130 Q131 R132 H133 Q139 N142 I143 S145 F146 I147 R149 S152 R161 P163 Y164 R168 G170 R171 V172 K173 N176

External links

PDB	RCSB:9bkd, PDBe:9bkd, PDBj:9bkd
PDBsum	9bkd
PubMed	39117603
UniProt	P46781\|RS9_HUMAN Small ribosomal subunit protein uS4 (Gene Name=RPS9)

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