Structure of PDB 9b6f Chain D

Receptor sequence
>9b6fD (length=929) Species: 10090 (Mus musculus) [Search protein sequence]
DLVNFIQANFKDAFGDIQFGKYLRLSCDTDSETLYELLTQHWHLKTPNLV
ISVTGGAKNFALKPRMRKIFSRLIYIAQSKGAWILTGGTHYGLMKYIGEV
VRDNTISENIVAIGIAAWGMVSNRDTLFSAQYIMLYILDNNHTHLLLVDN
GCHGHPTVEAKLRNQLEKYISERTSQDSNYGGKIPIVCFAQGGGRETLKA
INTSVKSKIPCVVVEGSGQIADVIASLVTSSMVKEKLVRFLPRTVSRLPE
EEIESWIKWLKEILESSHLLTVIKMEEAGDEIVSNAISYALYKAFSTNEQ
DKDNWNGQLKLLLEWNQLDLASDEIFTNDRRWESADLQEVMFTALIKDRP
KFVRLFLENGLNLQKFLTNEVLTELFSTHFSTLVYRNLQIAKNSYNDALL
TFVWKLVANFRRSRHPLQALFIWAILQNKKELSKVIWEQTKGCTLAALGA
SKLLKTLAKVKNDINAAGESEELANEYETRAVELFTECYSNDEDLAEQLL
VYSCEAWGGSNCLELAVEATDQHFIAQPGVQNFLSKQWYGEISRDTKNWK
IILCLFIIPLVGCGLVSFRKLWYYVAFFTSPFVVFSWNVVFYIAFLLLFA
YVLLMDFHSVPHTPELILYALVFVLFCDEVRQWYMNGVNYFTDLWNVMDT
LGLFYFIAGIVFRLHSSNKSSLYSGRVIFCLDYIIFTLRLIHIFTVSRNL
GPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGILRQNEQRWRWIFRSV
IYEPYLAMFGQVPSDVDSTTYDFSHCTFSGNESKPLCVELDEHNLPRFPE
WITIPLVCIYMLSTNILLVNLLVAMFGYTVGIVQENNDQVWKFQRYFLVQ
EYCNRLNIPFPFVVFAYFYMVVKKNETLAWEGVMKENYLVKINTKANDNS
EEMRHRFRQLDSKLNDLKSLLKEIANNIK
3D structure
PDB9b6f Mechanisms of sensory adaptation and inhibition of the cold and menthol receptor TRPM8.
ChainD
Resolution3.42 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1AIY D W877 L971 W724 L818
BS02 Y01 D L750 L843 N852 L597 L690 N699
BS03 Y01 D W682 I696 F735 S850 R851 W538 I552 F582 S697 R698
External links
PDB RCSB:9b6f, PDBe:9b6f, PDBj:9b6f
PDBsum9b6f
PubMed39093967
UniProtQ8R4D5|TRPM8_MOUSE Transient receptor potential cation channel subfamily M member 8 (Gene Name=Trpm8)

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